Would a mild second-degree burn be likely to heal by regeneration or fibrosis? Would the same type of healing take place in a third-degree burn that involved muscle tissue? Why or why not?
Explain what happens to dermal blood vessels when heat needs to be conserved (i.e., due to a cold environment).
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Key Concepts
Vasoconstriction
Thermoregulation
Hypothalamus
The disease pemphigus vulgaris involves a patient's own immune system attacking the desmosomes between the epithelial cells of the skin. What changes would you expect to see with this disease?
Number the strata of thick skin epidermis from deepest (1) to most superficial (5).
____Stratum spinosum
____Stratum corneum
____Stratum basale
____Stratum lucidum
____Stratum granulosum
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
Melanocytes account for the bulk of the epidermis.
Keratinocytes in the superficial strata of the epidermis die because:
a. They are too far away from the blood supply in the dermis.
b. They are surrounded by a lipid-based substance that makes them more permeable to water.
c. They do not die.
d. No keratinocytes in the epidermis are alive.
Nguyen comes to your clinic with a mole that has recently changed in appearance. You examine the mole and note that its borders are irregular, it has a deep blue-black color, and the color is unevenly distributed throughout the mole.
What is your immediate concern? Why?
