10. Hypothesis Testing for Two Samples

Smoking Cessation Programs

b. Does the difference between the success rate of the sustained care program and the standard care program appear to have practical significance?

Clinical Trials of OxyContin OxyContin (oxycodone) is a drug used to treat pain, but it is well known for its addictiveness and danger. In a clinical trial, among subjects treated with OxyContin, 52 developed nausea and 175 did not develop nausea. Among other subjects given placebos, 5 developed nausea and 40 did not develop nausea (based on data from Purdue Pharma L.P.). Use a 0.05 significance level to test for a difference between the rates of nausea for those treated with OxyContin and those given a placebo.

c. Does nausea appear to be an adverse reaction resulting from OxyContin?

Clinical Trials of OxyContin OxyContin (oxycodone) is a drug used to treat pain, but it is well known for its addictiveness and danger. In a clinical trial, among subjects treated with OxyContin, 52 developed nausea and 175 did not develop nausea. Among other subjects given placebos, 5 developed nausea and 40 did not develop nausea (based on data from Purdue Pharma L.P.). Use a 0.05 significance level to test for a difference between the rates of nausea for those treated with OxyContin and those given a placebo.

a. Use a hypothesis test.

A school administrator wants to compare the proportion of students who passed a standardized math exam in two different schools by taking samples from 2 classes. Assume the samples are random and independent. Calculate the $z$-score for testing whether there is a significant difference in the population proportions of student passing rates, but do not find a $P$-value or draw a conclusion for the hypothesis test.

Class A: 72 out of 120 students passed.

Class B: 65 out of 100 students passed.

In Exercises 29 and 30, (a) identify the claim and state Ho and Ha, (b) find the critical value(s) and identify the rejection region(s), (c) find the standardized test statistic z, (d) decide whether to reject or fail to reject the null hypothesis, and (e) interpret the decision in the context of the original claim. Assume the samples are random and independent.

A medical research team conducted a study to test the effect of a drug used to treat a type of inflammation. In the study, 68 subjects took the drug and 68 subjects took a placebo. The results are shown below. At α=0.05, can you reject the claim that the proportion of subjects who had at least 24 weeks of accrued remission is the same for the two groups? (Source: The New England Journal of Medicine)

For $x_1=34,n_1=50,x_2=52,$ & $n_2=75$, test the claim that for $\alpha =0.01$ using...

(A) A Hypothesis Test.

"Determining Sample Size An educator wants to determine the difference between the proportion of males and females who have completed four or more years of college. What sample size should be obtained if she wishes the estimate to be within 2 percentage points with 90% confidence, assuming that

b. she does not use any prior estimates?"

Denomination Effect A trial was conducted with 75 women in China given a 100-yuan bill, while another 75 women in China were given 100 yuan in the form of smaller bills (a 50-yuan bill plus two 20-yuan bills plus two 5-yuan bills). Among those given the single bill, 60 spent some or all of the money. Among those given the smaller bills, 68 spent some or all of the money (based on data from “The Denomination Effect,” by Raghubir and Srivastava, Journal of Consumer Research, Vol. 36). We want to use a 0.05 significance level to test the claim that when given a single large bill, a smaller proportion of women in China spend some or all of the money when compared to the proportion of women in China given the same amount in smaller bills.

b. Test the claim by constructing an appropriate confidence interval.

Seat Belt Use In a survey of 1000 drivers from the West, 934 wear a seat belt. In a survey of 1000 drivers from the Northeast, 909 wear a seat belt. At α=0.05, can you support the claim that the proportion of drivers who wear seat belts is greater in the West than in the Northeast? (Adapted from National Highway Traffic Safety Administration)

"[NW] Determining Sample Size A physical therapist wants to determine the difference in the proportion of men and women who participate in regular, sustained physical activity. What sample size should be obtained if she wishes the estimate to be within 3 percentage points with 95% confidence, assuming that

b. she does not use any prior estimates?"

Can Dogs Detect Malaria? A study was conducted to determine whether dogs could detect malaria from socks worn by malaria patients and socks worn by patients without malaria. Among 175 socks worn by malaria patients, the dogs made correct identifications 123 times. Among 145 socks worn by patients without malaria, the dogs made correct identifications 131 times (based on data presented at an annual meeting of the American Society of Tropical Medicine, by principal investigator Steve Lindsay). Use a 0.05 significance level to test the claim of no difference between the two rates of correct responses.

b. Test the claim by constructing an appropriate confidence interval.

Parks and Mental Health In Exercises 13–18, use the figure, which shows the percentages from a survey of two hundred 18- to 24-year-olds in the United States who say that various park and recreation activities have a positive impact on their mental health. (Adapted from National Recreation and Park Association)

Socializing and Taking Classes At α=0.05, can you support the claim that the proportion of 18- to 24-year-olds who benefit mentally from socializing in parks is different from the proportion who benefit mentally from taking classes in parks?