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Side-Chain Reactions of Substituted Pyridines
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Side-Chain Reactions of Substituted Pyridines
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27. Heterocycles / Side-Chain Reactions of Substituted Pyridines / Problem 3
Problem 3
Given the pKa values of benzylic carbanions (approximately 41) and pyridine carbanions (approximately 25), what can be inferred about their acidity?
A
Both carbanions have similar acidity as their pKa values are comparable
B
Pyridine carbanions are significantly more acidic than benzylic carbanions due to lower pKa values
C
Benzylic carbanions are more acidic because they have higher pKa values
D
Pyridine carbanions are less acidic because they have a higher pKa value
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