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23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides - Part 1 of 2!
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23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides - Part 1 of 2!
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23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides / Hydrolysis of Thioesters / Problem 6
Problem 6
Analyze the role of proton transfer in thioester hydrolysis under acidic conditions.
A
Proton transfer is only a minor step and does not affect the reaction outcome.
B
Proton transfer stabilizes the tetrahedral intermediate by redistributing charge.
C
Proton transfer results in the formation of a secondary thiol.
D
Proton transfer creates a new nucleophile in the reaction.
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