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Ch. 22 The Lymphatic System and Immunity
Martini - Fundamentals of Anatomy and Physiology 12th Edition
Martini, Nath, Bartholomew12th EditionFundamentals of Anatomy and PhysiologyISBN: 9780137854011Not the one you use?Change textbook
All textbooksMartini, Nath, Bartholomew 12th EditionCh. 22 The Lymphatic System and ImmunityProblem 14
Chapter 22, Problem 14

What are the three classes of lymphocytes, and where does each class originate?

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Identify the three main classes of lymphocytes: B cells, T cells, and natural killer (NK) cells.
Understand that all lymphocytes originate from hematopoietic stem cells in the bone marrow.
Recognize that B cells mature in the bone marrow itself, where they develop their antigen receptors.
Know that T cells migrate from the bone marrow to the thymus gland, where they mature and differentiate.
Acknowledge that natural killer (NK) cells also originate from the bone marrow but mature there without the need for thymic processing.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Classes of Lymphocytes

Lymphocytes are a type of white blood cell essential for immune responses. The three main classes are B cells, T cells, and Natural Killer (NK) cells, each with distinct roles in identifying and eliminating pathogens or infected cells.
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Classes of Antibodies

Origin of B Cells

B cells originate and mature in the bone marrow. They are responsible for producing antibodies that target specific antigens, playing a crucial role in humoral immunity.
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B Cell Receptors

Origin of T Cells and NK Cells

T cells develop in the thymus gland, where they mature and differentiate to perform cell-mediated immunity. NK cells also arise from the bone marrow but function in innate immunity by targeting virus-infected and tumor cells without prior sensitization.
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Regulatory T Cells
Related Practice
Textbook Question

List the specific functions of each of the body's primary and secondary lymphoid tissues and organs.

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Textbook Question

Blocking the antigen receptors on the surface of lymphocytes would interfere with

(a) Phagocytosis of the antigen

(b) That lymphocyte's ability to produce antibodies

(c) Antigen recognition

(d) The ability of the lymphocyte to present antigen

(e) Opsonization of the antigen

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Textbook Question

Compared with innate defenses, adaptive defenses

(a) Do not distinguish between one threat and another

(b) Are always present at birth

(c) Protect against threats on an individual basis

(d) Deny the entry of pathogens to the body

Textbook Question

CD4 markers are associated with

(a) Cytotoxic T cells

(b) Regulatory T cells

(c) Helper T cells

(d) All of these

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Textbook Question

What seven defenses, present at birth, provide the body with the defensive capability known as innate (nonspecific) immunity?

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Textbook Question

Give a function for each of the following:

(a) Cytotoxic T cells

(b) Helper T cells

(c) Regulatory T cells

(d) Plasma cells

(e) NK cells

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