2. Cell Chemistry & Cell Components
Nucleic Acids
- Textbook QuestionSingle strands of nucleic acids are directional, meaning that there are two different ends. What functional groups define the two different ends of a strand?3views
- Textbook Question
Mark the following properties as belonging to either DNA or RNA.
a. Contains the nucleotides A, G, C, and U _________
b. Found only in the nucleus of the cell _________
c. Can move in and out of the cell's nucleus _________
d. Contains two strands of nucleotides linked by hydrogen bonds _________
e. Contains the code for every protein in the body _________
f. Contains the sugar ribose _________
3views - Textbook QuestionMake a concept map (see BioSkills 12) that relates DNA's primary structure to its secondary structure. Your diagram should include deoxyribonucleotides, base-stacking interactions, purines, pyrimidines, phosphodiester linkages, DNA's primary structure, DNA's secondary structure, complementary base pairing, and antiparallel double helix.
- Multiple ChoiceWhich of the following describes a difference between DNA and RNA?1views
- Textbook QuestionWhat determines the primary structure of a DNA molecule?a. stem-and-loop configurationb. complementary base pairingc. deoxyribonucleotide sequenced. hydrophobic interactions and hydrogen bonding5views
- Multiple ChoiceWhich of the following are pyrimidines found in the nucleic acid DNA?3views
- Textbook QuestionIn the field of nanotechnology, DNA is used like Velcro to assemble tiny particles into structures that are < 0.0001 mm in size. Draw a model to illustrate how two particles (a circle and a square) could be brought together by linking them to short single-stranded DNA molecules. If the DNA sequence linked to the circle is GGATC, then provide the sequence linked to the square and identify the 5′ and 3′ ends of each strand.
- Textbook QuestionAccording to the RNA world model, a ribozyme would replicate by creating a double-stranded RNA intermediate. Would you expect the intermediate to have the same catalytic activity as the original ribozyme? Justify your answer with an explanation.
- Multiple ChoiceWhich of the following is true regarding complementary base pairing in DNA and RNA molecules?1views
- Multiple ChoiceBased on complementary base pairing, you would expect the percentage of __________ to be equal to the percentage of __________.2views
- Textbook QuestionEvaluate the following statements related to the synthesis of nucleic acids. Select True or False for each statement.T/F Ribonucleotides are added to the 3′ end of a DNA strand.T/F Polymerization of nucleic acids occurs by the formation of phosphodiester bonds.T/F Complementary pairing between sugars is required for copying nucleic acids.T/F Strands in a double helix are synthesized in an antiparallel orientation.2views
- Textbook Question
The drug methotrexate is used to treat several different types of cancer and diseases of the immune system. It works by inhibiting an enzyme in the cell necessary for folic acid synthesis. Without folic acid, the cell cannot make nucleotides. What, specifically, does an enzyme do in the cell? Why would inhibiting this enzyme disrupt folic acid synthesis? What effect would a disruption in folic acid synthesis have on the cell as a whole? (Hint: Think about the role that folic acid plays in the cell.) (Connects to Chapter 2)
- Multiple Choice
Which of the following statements about DNA structure is true?
2views - Textbook QuestionRNA and DNA are similar because .a. both are double-stranded helices;b. uracil is found in both of them;c. both contain the sugar deoxyribose;d. both are made up of nucleotides consisting of a sugar, a phosphate, and a base2views
- Multiple ChoiceWhich of the following lists represents the chemical components of a nucleotide?1views