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EAS Reactions of Pyridine
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EAS Reactions of Pyridine
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27. Heterocycles / EAS Reactions of Pyridine / Problem 3
Problem 3
Why is substitution at the c3 position in pyridine favored over the c2 position in EAS reactions?
A
Substitution at c3 stabilizes the negative charge on nitrogen.
B
Substitution at c3 avoids destabilizing positive charge development on nitrogen.
C
Substitution at c3 results in a more stable carbocation compared to c2.
D
Substitution at c3 leads to a more symmetrical product.
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