Organic Chemistry
Why is pyridine generally less reactive than benzene in electrophilic aromatic substitution (EAS) reactions?
Which of the following substituents, when attached to pyridine, would most likely increase its reactivity in EAS reactions?
Why is substitution at the c3 position in pyridine favored over the c2 position in EAS reactions?
Predict the major product of an EAS reaction between pyridine and bromine, considering pyridine's heteroatom preference for c3 substitution.
Which change in reaction conditions is most likely to increase the rate of an EAS reaction between pyridine and an electrophile?
