design-a-synthetic-route-to-obtain-n-butylbenzene-starting-from-benzene-comparin

Question

Design a synthetic route to obtain n-butylbenzene starting from benzene, comparing the outcomes of direct alkylation versus acylation followed by Clemensine reduction.

Accepted Answer

Acylation with butanoyl chloride followed by Clemensine reduction avoids rearrangement issues.

Answer

Both methods yield the same product with equal efficiency.

Answer

Direct alkylation is preferred because it uses fewer steps.

Answer

Direct alkylation with butyl chloride is faster and provides a higher yield.