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27. Heterocycles - Part 1 of 2!
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Problem 11
Problem 12
27. Heterocycles - Part 1 of 2!
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27. Heterocycles / Directing Effects in Substituted Pyrroles, Furans, and Thiophenes / Problem 11
Problem 11
Consider a pyrrole undergoing bromination. Which position is most likely to be brominated and why?
A
C3 position due to steric hindrance
B
C4 position due to resonance stabilization
C
C5 position due to inductive effects
D
C2 position due to the electron-donating nature of the nitrogen atom
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