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03:48A patient has an uncomplicated infection with a Gram-negative bacterium. He also has a history of penicillin allergy. Which drug is the best treatment option for this patient?
a. Ampicillin
b. A first-generation cephalosporin
c. A carbapenem
d. Isoniazid
e. Azithromycin
A patient who is not a healthcare worker is diagnosed with C. difficile pseudomembranous colitis. What most likely led to this infection?
a. The patient was recently treated with a bacteriostatic drug.
b. The patient was recently treated with a broad-spectrum drug.
c. The patient was treated with a bactericidal drug.
d. The patient recently became immune compromised and therefore had an increased risk for infection.
e. The patient was recently exposed to someone with an active C. difficile infection.
Choose the true statement(s) about therapeutic index (TI). Select all that apply.
a. A drug with a high therapeutic index would be effective above the dose at which it is potentially toxic.
b. A narrow TI is preferable.
c. A drug for which the maximum safe dose is close to the minimum effective dose would have a high TI.
d. It is one measure of a drug’s general safety.
e. A drug that is not selectively toxic would most likely have a high TI.
The difference between a synthetic drug and a semisynthetic drug is that
a. the semisynthetic drug is a modified synthetic drug.
b. the synthetic drug is a modified natural drug.
c. the synthetic drug is a modified semisynthetic drug.
d. the semisynthetic drug is a modified natural drug.
Match the antimicrobial drug class to its action. You may assign more than one drug class to a given action and some actions may not be applicable.
What advantages might a semisynthetic antimicrobial drug have over an antibiotic?
