20. Adaptive Immunity

Indicate whether each statement is true or false. If the statement is false, change the underlined word or phrase to make the statement true.

______Graft-versus-host disease can follow a bone marrow isograft.

Summarize the causes of immunodeficiencies. What is the effect of an immunodeficiency?

Where do T cells undergo self-tolerance selection?

Contrast autografts, isografts, allografts, and xenografts.

Compare and contrast the functions of four classes of immunosuppressive drugs.

Differentiate the three types of autoimmune diseases. Name an example of each type.

When a surgeon conducts a cardiac bypass operation by transplanting a piece of vein from a patient’s leg to the same patient’s heart, this is a(n):

a. Rejected graft

b. Autograft

c. Allograft

d. Type IV hypersensitivity

e. Cardiograft

Where do T cells undergo central tolerance selection?

Which of the following is NOT a consequence of the immune system lacking an immune tolerance?

What is immunological tolerance?

Label the four types of grafts on the accompanying figure.

In which of the following scenarios would administering immunoglobulins be useful? Select all that apply. (NCLEX/HESI/TEAS)

a. To neutralize a toxin

b. To aid a patient who is immune compromised

c. After venom exposure

d. To block IgM from crossing the placenta

e. To protect a premature infant from respiratory syncytial virus

The most important function of peripheral tolerance is to:

Explain what happens when a person develops a contact sensitivity to the poison oak plant.

a. What causes the observed symptoms?

b. How did the sensitivity develop?

c. How might this person be desensitized to poison oak?