A researcher is studying the pathogenesis of serum sickness, a classic type III hypersensitivity reaction. The following events are observed during the reaction:
1. Complement fragments promote chemotaxis of inflammatory cells
2. Antibodies bind soluble antigens to generate circulating immune complexes
3. Neutrophils release proteolytic enzymes that injure surrounding tissue
4. Small immune complexes become trapped in vessel walls and activate complement
5. Circulating immune complexes avoid efficient clearance by phagocytes
Which sequence correctly represents the progression of these events?