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Ch.12 Food as Fuel An Overview of Metabolism
Frost - General, Organic and Biological Chemistry 4th Edition
Frost4th EditionGeneral, Organic and Biological ChemistryISBN: 9780134988696Not the one you use?Change textbook
All textbooksFrost 4th EditionCh.12 Food as Fuel An Overview of MetabolismProblem 97e
Chapter 8, Problem 97e

Lauric acid, a saturated fatty acid, [12:0], is found in coconut oil.
e. How many cycles of β oxidation occur?

Verified step by step guidance
1
Step 1: Understand the concept of β oxidation. β oxidation is the metabolic process by which fatty acids are broken down in the mitochondria to generate acetyl-CoA, NADH, and FADH2. Each cycle of β oxidation removes two carbon atoms from the fatty acid chain in the form of acetyl-CoA.
Step 2: Identify the structure of lauric acid. Lauric acid is a saturated fatty acid with the formula C12H24O2. The [12:0] notation indicates it has 12 carbon atoms and no double bonds.
Step 3: Determine the number of acetyl-CoA molecules produced. Since each acetyl-CoA contains two carbon atoms, the total number of acetyl-CoA molecules produced from a 12-carbon fatty acid is calculated as \( \frac{12}{2} \).
Step 4: Calculate the number of β oxidation cycles. The number of β oxidation cycles is one less than the number of acetyl-CoA molecules produced because the final cycle produces two acetyl-CoA molecules. Use the formula \( \text{Number of cycles} = \text{Number of acetyl-CoA} - 1 \).
Step 5: Apply the formula to determine the number of β oxidation cycles for lauric acid. Substitute the number of acetyl-CoA molecules calculated in Step 3 into the formula from Step 4.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

β-Oxidation

β-Oxidation is a metabolic process that breaks down fatty acids to generate acetyl-CoA, which can then enter the citric acid cycle for energy production. This process occurs in the mitochondria and involves the sequential removal of two-carbon units from the fatty acid chain, starting from the carboxyl end.

Saturated Fatty Acids

Saturated fatty acids, like lauric acid, contain no double bonds between carbon atoms in their hydrocarbon chain. This structure allows them to pack closely together, resulting in a solid state at room temperature. The absence of double bonds also influences their metabolic pathways, including the number of β-oxidation cycles they undergo.
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Fatty Acid Chain Length

The length of a fatty acid chain significantly affects the number of β-oxidation cycles it undergoes. Lauric acid, with a 12-carbon chain, will undergo a specific number of cycles based on its length, as each cycle removes two carbons. Understanding the chain length is crucial for calculating the total cycles of β-oxidation and the resulting acetyl-CoA production.
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Related Practice
Textbook Question

Lauric acid, a saturated fatty acid, [12:0], is found in coconut oil.

a. Draw fatty acyl lauric acid activated for β oxidation.

Textbook Question

Excess nitrogen in the body can form uric acid crystals responsible for the painful condition called gout. Besides proteins, name a biomolecule synthesized in the body that uses nitrogen.

Textbook Question

Can acetyl CoA feed into gluconeogenesis, producing glucose for the body? Can fatty acids be used to produce glucose?

Textbook Question

Consider the complete oxidation of arachidic acid, a saturated fatty acid, [20:0].

b. How many cycles of β oxidation occur?

Textbook Question

A person is brought to the emergency room in what appears to be a drunken stupor. On closer examination, she seems to be breathing very rapidly and you notice a sweet-smelling odor on her breath. You find out this person has not been drinking alcohol. What is her likely condition?

Textbook Question

Consider the complete oxidation of capric acid, a saturated fatty acid, [10:0].

c How many ATP are generated from the complete oxidation of capric acid?