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Key Concepts in Cell Structure, Membrane Transport, and Cellular Respiration

Study Guide - Smart Notes

Tailored notes based on your materials, expanded with key definitions, examples, and context.

  • Intermediate filaments provide structural support to cells, maintaining their shape and mechanical stability.

  • Gap junctions, primarily composed of connexins, enable direct cytoplasmic exchange of ions and small molecules between adjacent cells, facilitating coordinated cellular responses.

  • Cholesterol is essential for maintaining plasma membrane integrity and stability.

  • Collagen is not a transport protein; examples of transport proteins include aquaporins, proton pumps, and potassium channels.

  • Hypotonic solutions can cause water to move into the cell, potentially leading to cell swelling (not shrinkage).

  • Pinocytosis is the type of endocytosis where cells engulf small droplets of extracellular fluid and dissolved solutes to form small vesicles for internalization.

  • The sodium-calcium exchanger is an example of an antiporter, exchanging sodium and calcium ions in opposite directions across the membrane.

  • Glucose typically requires facilitated diffusion to cross the cell membrane, as it is a large, polar molecule.

  • Secondary active transport depends on the energy stored as an ion gradient by primary active transport, rather than directly using ATP.

  • Endocytosis involves inward budding of the plasma membrane, facilitated by clathrin and dynamin, while exocytosis involves vesicle fusion with the plasma membrane, mediated by SNARE proteins and synaptotagmin.

  • Physical changes, such as water freezing, are not chemical reactions; burning paper and cooking are chemical reactions.

  • ATP is the energy currency of the cell, not genetic material or a DNA subunit.

  • DNA polymerase is the enzyme responsible for synthesizing DNA during cell replication.

  • Enzymes decrease the activation energy of chemical reactions, increasing the reaction rate. Eacatalyzed<Eauncatalyzed

  • Cofactors are not consumed during enzyme catalysis; they assist enzymes and can be organic or inorganic.

  • Competitive inhibitors bind to the active site of enzymes, blocking substrate binding.

  • Metabolic pathways process substrates through multiple intermediate steps to produce final products.

  • The correct order of aerobic cellular respiration stages is: Glycolysis → Pyruvate oxidation → Krebs cycle → Electron transport chain and chemiosmosis.

  • In chemiosmosis, ions diffuse from high to low concentration across a membrane.

  • Glycolysis breaks down sugar molecules (glucose) into pyruvate and occurs in the cytoplasm, not the mitochondria, and does not require oxygen.

  • At the end of pyruvate oxidation, the two carbon atoms from pyruvate are attached to CoA, forming acetyl-CoA.

  • After hydrolysis, maltose (a disaccharide) yields two glucose molecules, each entering the Krebs cycle twice, for a total of four cycles.

  • Electrons from NADH2 ultimately react with oxygen at the end of the electron transport chain, forming water. NADH2+O2→H2O

  • An uncoupling agent that diminishes the proton gradient across cristae leads to decreased production of ATP.

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