Which statement correctly compares the signaling mechanisms of hormones and nitric oxide?

Hormones require transport proteins to enter the cell, while nitric oxide does not.

Both hormones and nitric oxide are degraded by lysosomes after signaling.

Both hormones and nitric oxide diffuse across the plasma membrane and bind to intracellular receptors.

Nitric oxide binds to nuclear receptors, while hormones bind to cytoplasmic proteins.