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Ch. 15 - Innate Immunity
Bauman - Microbiology with Diseases by Taxonomy 6th Edition
Bauman6th EditionMicrobiology with Diseases by TaxonomyISBN: 9780134832302Not the one you use?Change textbook
All textbooksBauman 6th EditionCh. 15 - Innate ImmunityProblem 3
Chapter 15, Problem 3

Indicate which statements are true. Correct all false statements by changing the underlined words.
__________ Wandering macrophages experience diapedesis.

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Understand the key terms: 'wandering macrophages' are macrophages that move through tissues, and 'diapedesis' is the process by which white blood cells move from the bloodstream through the endothelial cells of blood vessels into tissues.
Recall that diapedesis specifically refers to the movement of cells from the blood vessels into tissues, not the movement of cells already in the tissue.
Recognize that wandering macrophages are already located within tissues and do not undergo diapedesis; instead, it is their precursor cells, such as monocytes in the blood, that undergo diapedesis to enter tissues and then differentiate into macrophages.
Therefore, the statement 'Wandering macrophages experience diapedesis' is false because wandering macrophages do not cross blood vessel walls; monocytes do.
Correct the statement by replacing 'Wandering macrophages' with 'Monocytes' to read: 'Monocytes experience diapedesis.'

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Diapedesis

Diapedesis is the process by which white blood cells, such as macrophages and neutrophils, move out of the bloodstream by squeezing through the endothelial cells of blood vessel walls to reach sites of infection or injury.
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3) Vasodilation

Wandering Macrophages

Wandering macrophages are mobile immune cells that patrol tissues to detect and engulf pathogens or debris. They originate from monocytes that have left the bloodstream and differentiate within tissues.
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Functions of Helper T Cells (TH):Activation of Macrophages

Relationship Between Diapedesis and Wandering Macrophages

Monocytes, not wandering macrophages, undergo diapedesis to exit blood vessels. Once in tissues, they differentiate into wandering macrophages, which then move freely but do not perform diapedesis themselves.
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Symbiotic Relationships
Related Practice
Textbook Question

The complement system involves:

a. The production of antigens and antibodies

b. Serum proteins involved in nonspecific defense

c. A set of genes that distinguish foreign cells from body cells

d. The elimination of undigested remnants of microorganisms

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Textbook Question

Identify the type of hypersensitivity reaction in each photo.

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Textbook Question

How does a phagocyte “know” it is in contact with a pathogen instead of another body cell?

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Textbook Question

Indicate which statements are true. Correct all false statements by changing the underlined words.

__________ The surface cells of mucous membranes are alive.

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Textbook Question

The alternative complement activation pathway involves:

a. Factors B, D, and P

b. The cleavage of C5 to form C9

c. Binding to mannose sugar

d. Recognition of antigens bound to specific antibodies

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Textbook Question

Indicate which statements are true. Correct all false statements by changing the underlined words.

__________ Monocytes are immature macrophages.

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