20. Adaptive Immunity

Which of the following is NOT an immunoglobin class?

Which of the following antibodies is involved in causing basophils to release histamine when the antibody encounters an allergen?

Match the following antibody classes with their description: 

a) IgA.

b)  IgG.

c)  IgE.

___ First antibody produced during primary response. 

___ Protects mucous membranes.  

___ Most abundant antibody. 

___ Found on the surface of B cells. 

___ Triggers allergic reactions to allergens.

The primary B-cell receptor is:

______ is the first immunoglobulin class produced during a primary response.

Match the following choices to the statements in questions 5–7:

a. IgA

b. IgD

c. IgE

d. IgG

e. IgM

The first antibodies synthesized; especially effective against microorganisms.

The major class of immunoglobulin found on the surfaces of the walls of the intestines and airways is secretory:

a. IgG

b. IgM

c. IgA

d. IgE

e. IgD

The major inflammatory mediator released by degranulating mast cells in type I hypersensitivity is:

a. Immunoglobulin

b. Complement

c. Histamine

d. Interleukin

e. Prostaglandin

Why is a person who produces a large amount of IgE more likely to experience anaphylactic shock than a person who instead produces a large amount of IgG?

What is IgA protease, and what effect would it possibly have on host immune function?

List the antibody isotype(s) that exhibit the stated feature. Some features will be assigned to more than one antibody.

Feature:

Most abundant antibody in serum

Made as a dimer

Stimulates allergic responses

Does not cross the placenta

Considered a complement activator

Rare antibody that’s poorly characterized

Main antibody in breast milk and mucus

Dominates the secondary immune response

Made early in the course of infection

Made in a primary immune response

Which antibody class crosses the placenta from mother to child?

Match the following choices to the statements in questions 5–7:

a. IgA

b. IgD

c. IgE

d. IgG

e. IgM

Antibodies that protect the fetus and newborn.

Which type of hypersensitivity is not antibody mediated?

a. Type I hypersensitivities

b. Type II hypersensitivities

c. Type III hypersensitivities

d. Type IV hypersensitivities

e. Antibodies mediate all of these.

Each class of antibody is specifically defined by its