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Ch. 7 - Microbial Genetics
Bauman - Microbiology with Diseases by Taxonomy 6th Edition
Bauman6th EditionMicrobiology with Diseases by TaxonomyISBN: 9780134832302Not the one you use?Change textbook
Chapter 7, Problem 4

Which of the following forms ionic bonds with eukaryotic DNA and stabilizes it?
a. Chromatin
b. Bacteriocin
c. Histone
d. Nucleoid

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1
Understand the nature of the question: It asks which molecule forms ionic bonds with eukaryotic DNA to stabilize it. This involves knowledge of DNA structure and associated proteins in eukaryotic cells.
Recall that eukaryotic DNA is wrapped around proteins to form a complex called chromatin, which helps in packaging and stabilizing DNA within the nucleus.
Identify the key proteins involved in chromatin structure: Histones are positively charged proteins that bind to the negatively charged phosphate backbone of DNA through ionic bonds.
Evaluate the options: Chromatin is the complex of DNA and proteins, bacteriocins are antibacterial proteins, histones are the DNA-binding proteins, and nucleoid refers to the DNA region in prokaryotes.
Conclude that the molecule forming ionic bonds with eukaryotic DNA to stabilize it is the histone protein.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Histones and DNA Interaction

Histones are positively charged proteins that bind to the negatively charged phosphate backbone of eukaryotic DNA through ionic bonds. This interaction helps package DNA into a compact, stable structure called chromatin, facilitating gene regulation and protection.
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Chromatin Structure

Chromatin is the complex of DNA and proteins, mainly histones, found in the nucleus of eukaryotic cells. It organizes DNA into nucleosomes, allowing efficient packaging and playing a key role in controlling gene expression and DNA stability.
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Differences Between Eukaryotic and Prokaryotic DNA Organization

Eukaryotic DNA is wrapped around histones forming chromatin, whereas prokaryotic DNA is organized in a nucleoid without histones. Understanding this distinction is crucial to identify which molecules stabilize DNA in different organisms.
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Prokaryotic & Eukaryotic Cells