Multiple Choice
Which of the following microscope slides shows C. diphtheriae?
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Table of contents
- 1. Introduction to Microbiology3h 27m
- Introduction to Microbiology18m
- Introduction to Taxonomy26m
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30. Microbial Infections - Respiratory System
Diphtheria
Multiple Choice
Not all Corynebacterium diphtheriae cause diphtheria. What is different about the bacteria that do?
A
They contain cord factor as part of the mycolic acid component of their cell wall.
B
They have been infected with a phage that codes for an exotoxin.
C
They infect the alveoli rather than being sequestered to the upper respiratory tract.
D
They are part of a pseudomembrane, which allows them to become established in the airway more easily.
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Verified step by step guidance1
Understand that not all strains of Corynebacterium diphtheriae cause diphtheria because the disease-causing ability depends on a specific factor.
Recognize that the key difference lies in the presence of a gene that encodes for the diphtheria toxin, which is responsible for the symptoms of diphtheria.
Know that this gene is not originally part of the bacterial chromosome but is introduced into the bacteria by a bacteriophage (a virus that infects bacteria).
Therefore, only Corynebacterium diphtheriae strains that have been lysogenized by this phage carry the gene for the exotoxin and can produce the toxin.
Conclude that the presence of the phage-encoded exotoxin gene is what differentiates toxigenic (disease-causing) strains from non-toxigenic strains.
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