Textbook Question
Consider the following segment of mRNA produced by the normal order of DNA nucleotides:
ACA UCA CGG GUA
b. What is the amino acid order if a point mutation changes UCA to ACA?
Ch.17 Nucleic Acids and Protein Synthesis
Timberlake14th EditionChemistry: An Introduction to General, Organic, and Biological ChemistryISBN: 9781292472249
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Table of contents
- Ch.1 Chemistry in Our Lives19
- Ch.2 Chemistry and Measurements80
- Ch.3 Matter and Energy53
- Ch.4 Atoms and Elements58
- Ch.5 Nuclear Chemistry42
- Ch.6 Ionic and Molecular Compounds57
- Ch.7 Chemical Quantities and Reactions38
- Ch.8 Gases30
- Ch.9 Solutions50
- Ch.10 Acids and Bases and Equilibrium64
- Ch.11 Introduction to Organic Chemistry: Hydrocarbons77
- Ch.12 Alcohols, Thiols, Ethers, Aldehydes, and Ketones82
- Ch.13 Carbohydrates54
- Ch.14 Carboxylic Acids, Esters, Amines, and Amides91
- Ch.15 Lipids61
- Ch.16 Amino Acids, Proteins, and Enzymes84
- Ch.17 Nucleic Acids and Protein Synthesis86
- Ch.18 Metabolic Pathways and ATP Production73
Timberlake14th EditionChemistry: An Introduction to General, Organic, and Biological ChemistryISBN: 9781292472249Not the one you use?Change textbook
Chapter 17, Problem 65a
Consider the following segment of mRNA produced by the normal order of DNA nucleotides:
ACA UCA CGG GUA
a. What is the amino acid order produced from this mRNA?
Verified step by step guidance1
Identify the codons in the given mRNA sequence. A codon is a sequence of three nucleotides. For the given mRNA sequence 'ACA UCA CGG GUA', the codons are: ACA, UCA, CGG, and GUA.
Use the genetic code table to determine the amino acid corresponding to each codon. For example, ACA corresponds to threonine (Thr), UCA corresponds to serine (Ser), CGG corresponds to arginine (Arg), and GUA corresponds to valine (Val).
Write the amino acid sequence in the order determined by the codons. The sequence will be Thr-Ser-Arg-Val.
Ensure that the sequence is written in the correct N-terminus to C-terminus direction, as this is the standard convention for representing amino acid sequences.
Double-check the codon-to-amino acid translation using the genetic code table to ensure accuracy in the amino acid sequence.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
mRNA Translation
mRNA translation is the process by which ribosomes synthesize proteins based on the sequence of nucleotides in mRNA. Each set of three nucleotides, known as a codon, corresponds to a specific amino acid. Understanding this process is crucial for determining the amino acid sequence encoded by the mRNA.
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1:42
Introduction to Translation Concept 1
Codons and Amino Acids
Codons are sequences of three nucleotides in mRNA that specify a particular amino acid during protein synthesis. The genetic code, which is universal among most organisms, maps each codon to its corresponding amino acid. For example, the codon 'ACA' codes for threonine, while 'UCA' codes for serine.
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3:03Amino Acid Catabolism: Amino Group Example 2
Genetic Code
The genetic code is a set of rules that defines how sequences of nucleotides in DNA and RNA are translated into proteins. It consists of 64 codons that encode 20 amino acids, along with start and stop signals for protein synthesis. Familiarity with the genetic code is essential for interpreting mRNA sequences and predicting the resulting amino acid chains.
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Related Practice
Textbook Question
Consider the following segment of mRNA produced by the normal order of DNA nucleotides:
ACA UCA CGG GUA
e. What is the amino acid order if an insertion mutation adds a G to the beginning of the mRNA segment?
Textbook Question
Consider the following segment of mRNA produced by the normal order of DNA nucleotides:
ACA UCA CGG GUA
f. What is the amino acid order if a deletion mutation removes the A at the beginning of the mRNA segment?
Textbook Question
What is the effect of a deletion mutation on the amino acid sequence of a polypeptide?
Textbook Question
How is protein synthesis affected if the normal base sequence TTT in the DNA template strand is changed to TTC?
Textbook Question
The following is a segment of the DNA template that codes for human insulin: TTT GTG AAC CAA CAC CTG
b. Write the three-letter and one-letter abbreviations for this corresponding peptide segment.