If the sodium concentration in blood plasma is 0.140 M, and Ksp for sodium urate is 5.76 * 10^-8, what minimum concentration of urate would result in precipitation?

Name: Chemistry: A Molecular Approach
Author: Tro
ISBN: 9780134874371

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Identify the chemical equilibrium involved: NaC5H3N4O3 (s) ⇌ Na^+ (aq) + C5H3N4O3^- (aq).

Write the expression for the solubility product constant (K_{sp}): K_{sp} = [Na^+][C5H3N4O3^-].

Substitute the given values into the K_{sp} expression: 5.76 \(\times\) 10^{-8} = (0.140)[C5H3N4O3^-].

Solve for the concentration of urate ion, [C5H3N4O3^-], by dividing K_{sp} by the sodium ion concentration: [C5H3N4O3^-] = \(\frac{5.76 \times 10^{-8}\)}{0.140}.

Interpret the result: The calculated [C5H3N4O3^-] is the minimum concentration of urate required for precipitation to occur.

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Solubility Product Constant (Ksp)

The solubility product constant (Ksp) is an equilibrium constant that applies to the solubility of ionic compounds. It represents the maximum product of the molar concentrations of the ions in a saturated solution at a given temperature. For sodium urate, Ksp indicates the point at which the solution becomes saturated, and any additional solute will precipitate out of the solution.

Precipitation Reaction

A precipitation reaction occurs when two soluble salts react in solution to form an insoluble product, or precipitate. In this context, when the concentration of urate ions exceeds a certain threshold, determined by the Ksp, sodium urate will begin to form solid crystals, indicating that the solution is supersaturated with respect to that compound.

Equilibrium Concentrations

Equilibrium concentrations refer to the concentrations of reactants and products in a chemical reaction at equilibrium. In the case of sodium urate, the equilibrium expression derived from Ksp allows us to calculate the minimum concentration of urate ions needed to reach the saturation point, where the product of the concentrations of sodium and urate equals the Ksp value.

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