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Extracellular Matrix of Animal Cells definitions

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  • Extracellular Matrix
    A network of fibers and proteins outside cells, providing structural support and connecting cells within tissues.
  • Collagen Fibrils
    Strong, fibrous structures formed from collagen, essential for connective tissue strength and integrity.
  • Fibroblasts
    Specialized cells responsible for producing collagen, contributing to the formation of connective tissues.
  • Elastin
    A flexible protein fiber that imparts elasticity to tissues, crucial for organs like skin to stretch and recoil.
  • Fibronectins
    Glycoproteins that link collagen fibers to cells, facilitating cell-matrix adhesion and tissue organization.
  • Glycoproteins
    Molecules composed of proteins and sugars, playing roles in cell adhesion and extracellular matrix structure.
  • Glycosaminoglycans
    Long carbohydrate chains that bind matrix components, contributing to tissue consistency and hydration.
  • Hyaluron
    A specific glycosaminoglycan that fills extracellular space, providing viscosity and structural support.
  • Integrins
    Transmembrane proteins connecting the cytoskeleton to the extracellular matrix, mediating adhesion and signaling.
  • Cytoskeleton
    An internal cellular framework that interacts with integrins to anchor cells to the extracellular matrix.
  • Anchorage-dependent Growth
    A process where cells require attachment to the extracellular matrix via integrins to proliferate.
  • Connective Tissue
    Tissue type rich in extracellular matrix components, providing support and cohesion for cells.
  • Active Conformation
    A structural state of integrins that enables binding to the extracellular matrix and cellular signaling.
  • Inactive Conformation
    A bent state of integrins where they do not interact with the extracellular matrix or transmit signals.