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Multiple Choice
Which of the following best describes a nucleosome?
A
A segment of DNA wrapped around a core of histone proteins
B
A double-membraned structure that contains the cell's genetic material
C
A membrane-bound organelle responsible for protein synthesis
D
A vesicle involved in the breakdown of cellular waste
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Verified step by step guidance
1
Understand the term 'nucleosome': A nucleosome is a structural unit of chromatin in eukaryotic cells, consisting of DNA wrapped around histone proteins.
Recall the role of histone proteins: Histones are positively charged proteins that help package negatively charged DNA into a compact structure, enabling efficient storage within the nucleus.
Visualize the structure: A nucleosome consists of approximately 147 base pairs of DNA wrapped around a core of eight histone proteins (two each of H2A, H2B, H3, and H4). This structure resembles 'beads on a string' when viewed under a microscope.
Eliminate incorrect options: The other options describe unrelated cellular structures or functions, such as double-membraned organelles (e.g., nucleus), protein synthesis (e.g., ribosomes), and waste breakdown (e.g., lysosomes).
Conclude that the correct description of a nucleosome is 'A segment of DNA wrapped around a core of histone proteins,' as this matches the biological definition and structure of a nucleosome.