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Multiple Choice
In one turn of the citric acid cycle per acetyl-CoA (excluding NADH produced by pyruvate dehydrogenase), how many molecules of NADH are produced?
A
B
C
D
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Verified step by step guidance
1
Recall that the citric acid cycle (Krebs cycle) processes one acetyl-CoA molecule per turn.
Identify the specific steps in the cycle where NADH is produced: these are the reactions catalyzed by isocitrate dehydrogenase, α-ketoglutarate dehydrogenase, and malate dehydrogenase.
Count the number of NADH molecules generated at each of these steps per acetyl-CoA molecule; each of these enzymes produces one NADH molecule per turn.
Sum the NADH molecules produced at these three steps to find the total NADH produced per turn of the cycle (excluding NADH from pyruvate dehydrogenase).
Conclude that the total number of NADH molecules produced per acetyl-CoA in one turn of the citric acid cycle is the sum from step 4.