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Ch. 21 The Immune System: Innate and Adaptive Body Defenses
Marieb - Human Anatomy & Physiology 7th Edition
Marieb, Hoehn7th EditionHuman Anatomy & PhysiologyISBN: 9780805359091Not the one you use?Change textbook
Chapter 20, Problem 7b

Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
Phagocytic cells of innate immunity include NK cells and basophils.

Verified step by step guidance
1
Step 1: Understand the role of phagocytic cells in innate immunity. Phagocytic cells are specialized cells that engulf and digest pathogens, debris, and other harmful particles. Examples include neutrophils, macrophages, and dendritic cells.
Step 2: Analyze the statement provided. The statement claims that NK (natural killer) cells and basophils are phagocytic cells of innate immunity.
Step 3: Recall the functions of NK cells and basophils. NK cells are part of innate immunity but are not phagocytic; they destroy infected or cancerous cells by inducing apoptosis. Basophils are also part of innate immunity but are involved in releasing histamine and other chemicals during allergic reactions and inflammation, not phagocytosis.
Step 4: Determine the accuracy of the statement. Based on the functions of NK cells and basophils, the statement is false because neither NK cells nor basophils are phagocytic.
Step 5: Correct the false statement. A true statement would be: 'Phagocytic cells of innate immunity include neutrophils, macrophages, and dendritic cells.'

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Innate Immunity

Innate immunity is the body's first line of defense against pathogens, consisting of physical barriers and immune cells that respond quickly to infections. It includes various cell types, such as phagocytes, which engulf and destroy foreign invaders. Unlike adaptive immunity, innate immunity does not require prior exposure to a pathogen to be activated.
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Phagocytic Cells

Phagocytic cells are a type of immune cell that can engulf and digest pathogens and debris. Key examples include macrophages and neutrophils, which play a crucial role in the innate immune response. These cells recognize, ingest, and destroy harmful microorganisms, helping to prevent the spread of infection.
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Natural Killer (NK) Cells

Natural Killer (NK) cells are a subset of lymphocytes that play a vital role in the innate immune system by targeting and destroying infected or cancerous cells. Unlike phagocytes, NK cells do not engulf pathogens; instead, they release cytotoxic substances that induce apoptosis in their targets. They are essential for early defense against viral infections and tumor surveillance.
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