Textbook Question
Class I MHC molecules display_____antigens and activate_____cells. Class II MHC molecules display _____antigens and activate_____cells.
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Ch. 20 The Lymphatic System and Immunity
Amerman3rd EditionHuman Anatomy & PhysiologyISBN: 9780138247201, 9780138247928, 9780138201814
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Table of contents
- Ch. 1 Introduction to Anatomy and Physiology24
- Ch. 2 The Chemistry of Life37
- Ch. 3 The Cell54
- Ch. 4 Histology46
- Ch. 5 The Integumentary System30
- Ch. 6 Bones and Bone Tissue36
- Ch. 7 The Skeletal System40
- Ch. 8 Articulations19
- Ch. 9 The Muscular System35
- Ch. 10 Muscle Tissue and Physiology29
- Ch. 11 Introduction to the Nervous System and Nervous Tissue28
- Ch. 12 The Central Nervous System41
- Ch. 13 The Peripheral Nervous System41
- Ch. 14 The Autonomic Nervous System and Homeostasis31
- Ch. 15 The Special Senses39
- Ch. 16 The Endocrine System42
- Ch. 17 The Cardiovascular System I: The Heart28
- Ch. 18 The Cardiovascular System II: The Blood Vessels43
- Ch. 19 Blood32
- Ch. 20 The Lymphatic System and Immunity41
- Ch. 21 The Respiratory System27
- Ch. 22 The Digestive System27
- Ch. 23 Metabolism and Nutrition7
- Ch. 24 The Urinary System39
- Ch. 25 Fluid, Electrolyte, and Acid-Base Homeostasis39
- Ch. 26 The Reproductive System10
- Ch. 27 Development and Heredity5
Amerman3rd EditionHuman Anatomy & PhysiologyISBN: 9780138247201, 9780138247928, 9780138201814Not the one you use?Change textbook
Chapter 20, Problem 16
Which of the following is not a role of TH cells?
a. Stimulation of macrophages
b. Activation of naïve TC cells
c. Stimulation of naïve B cells
d. Stimulation of clonal selection
Verified step by step guidance1
Understand the role of TH cells (Helper T cells) in the immune system. TH cells are a type of lymphocyte that play a central role in adaptive immunity by coordinating the activity of other immune cells.
Review the specific functions of TH cells: they stimulate macrophages to enhance phagocytosis, activate naïve TC cells (cytotoxic T cells) to target infected or abnormal cells, and stimulate naïve B cells to produce antibodies.
Learn about clonal selection, which refers to the process where specific B or T cells are selected and proliferate in response to an antigen. TH cells indirectly support clonal selection by activating B cells and TC cells, but they do not directly stimulate clonal selection.
Compare each option provided in the question to the known roles of TH cells. Identify which option does not align with their direct functions.
Conclude that the correct answer is the option that describes a process TH cells do not directly perform, based on the understanding of their roles in the immune system.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
T Helper Cells (T<sub>H</sub> cells)
T Helper cells are a subset of T lymphocytes that play a crucial role in the immune response by activating and regulating other immune cells. They assist in the activation of B cells, enhance the activity of macrophages, and help in the activation of cytotoxic T cells. Their primary function is to coordinate the immune response, making them essential for effective immunity.
Recommended video:
4:27
Review of Cytotoxic vs Helper T Cells
Clonal Selection
Clonal selection is a fundamental process in the adaptive immune system where specific lymphocytes are activated and proliferate in response to an antigen. This process ensures that the immune system produces a large number of cells that can specifically target and eliminate pathogens. T<sub>H</sub> cells are involved in this process by providing necessary signals to B cells and T<sub>C</sub> cells.
Recommended video:
6:43Clonal Selection
Naïve T and B Cells
Naïve T and B cells are immature lymphocytes that have not yet encountered their specific antigen. Naïve T cells require activation by T<sub>H</sub> cells to differentiate into effector cells, while naïve B cells need stimulation from T<sub>H</sub> cells to produce antibodies. Understanding the roles of these cells is essential for grasping how the immune system mounts a response to infections.
Recommended video:
3:11B cell Activation by T Independent Antigens
Related Practice
Textbook Question
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
Dendritic cells may activate both TH and TC cells.
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Textbook Question
On which type(s) of cells are class I MHC molecules located?
a. Antigen-presenting cells only
b. B cells only
c. All nucleated body cells
d. Antigen-presenting cells and B cells
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Textbook Question
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
The cells involved in organ and transplant rejection are primarily B cells.
Textbook Question
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
The immune response to a viral infection involves NK cells and different kinds of lymphocytes.
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Textbook Question
Explain how active immunity and passive immunity differ.
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