Imagine that a disease turns the simple epithelia of the lungs, kidney tubules, and intestines into keratinized stratified squamous epithelia. What effect would this change in form have on the functions of these tissues?
Epithelial cells of the kidneys have pumps that drive the transcellular transport of sodium ions.
Is this epithelium likely to be simple or stratified? Why?
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Key Concepts
Epithelial Tissue Types
Transcellular Transport
Function of Kidney Epithelium
Certain types of cancerous lung tumors can secrete hormones normally made by the pancreas, adrenal gland, and hypothalamus. What prevents such secretion from happening in healthy cells?
If you were to cut through epithelial tissue without penetrating the basement membrane, would you expect bleeding to occur? Why or why not?
In the disease scleroderma, excessive collagen, glycosaminoglycans, and glycoproteins are produced and deposited in tissues throughout the body. Predict the effects of this disease.
In the disease pulmonary fibrosis, elastic fibers of the lung are destroyed and replaced with collagen fibers. Predict the effect this would have on breathing.
Predict which organelles are likely to be abundant in cells such as fibroblasts that actively produce and secrete proteins.
